FIELD: chemistry of organometallic compounds, chemical technology.
SUBSTANCE: invention relates to the improved method for preparing the chelate compound bis-(1-vinylimidazole)zinc diacetate (I) representing the medicinal preparation of acizol that is the effective antidote and antioxidant. Method for preparing the compound (I) is carried out in the absence of organic solvents at temperature 20-35°C in the mole ratio 1-vinylimidazole : zinc diacetate in the range from 10:1 to 3:1. Method provides exclusion fire hazard and explosion hazard solvent from the technological process and enhancement of the yield of highly pure acizol satisfied for Pharmacopoeia requirements.
EFFECT: improved method for preparing.
2 cl, 4 ex
| Title |
Year |
Author |
Number |
| METHOD FOR PREPARING PHARMACOPOEIA BIS-(1-VINYLAMIDAZOLE)-ZINC DIACETATE |
2006 |
- Trofimov Boris Aleksandrovich
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- Nechiporenko Sergej Petrovich
- Nekrasov Mikhail Sergeevich
- Pronina Natal'Ja Vasil'Evna
- Khamidullin Nail' Mansurovich
- Barinov Vladimir Aleksandrovich
|
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|
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