ANTIDOTE OF CARBON MONOXIDE AND METHOD OF ITS APPLICATION Russian patent published in 2011 - IPC A61K31/315 A61K31/133 A61K33/30 A61P39/02 

Abstract RU 2425676 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to zinc-containing antidote of lethal and severe poisonings with carbon monoxide. Claimed antidote represents intramolecular tricyclic complex of triethanolamine with zinc salts of inorganic or organic acids (2, 8, 9-trihydrozincatrane) with ratio of triethanolamine to zinc salts being 1:1. Invention also relates to method of protection against poisoning by carbon monoxide by peroral introduction into organism of zinc-containing antidote in 5 vol. % ethanol in dose range 20-60 mg/kg of body weight.

EFFECT: prevention of lethal poisoning with carbon monoxide, higher efficiency and reducing acute toxicity of zinc-containing antidote.

9 cl, 5 ex.

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RU 2 425 676 C1

Authors

Voronkov Mikhail Grigor'Evich

Fedorin Andrej Jur'Evich

Mashanov Anton Vladimirovich

Malyshkina Natal'Ja Aleksandrovna

Kuznetsova Galina Alekseevna

Jushkov Gennadij Georgievich

Dates

2011-08-10Published

2010-05-11Filed