METHOD FOR ENHANCING SPECIFIC ACTIVITY OF ANTIBODY OF IGG CLASS Russian patent published in 2005 - IPC

Abstract RU 2254874 C2

FIELD: medicinal biotechnology, immunology.

SUBSTANCE: invention relates to producing medicinal biological preparations. Invention relates to a method for enhancing specific activity of immunoglobulins of class G. Method involves freezing immunoglobulin G-containing fractions to temperature from -20°C to -196°C and subjected for gamma-irradiation in doses 5-50 kGr with power of absorbed dose 60-110 Gr/min. method provides elevating the specific activity of immunoglobulin G, increasing titer, avidity and reducing anti-complementary activity.

EFFECT: improved method for elevating activity of antibodies.

3 tbl, 3 dwg, 4 ex

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RU 2 254 874 C2

Authors

Nigmatullin T.G.

Atangulova R.G.

Israfilov A.G.

Mostovskaja E.V.

Shafieva R.S.

Dates

2005-06-27Published

2003-07-25Filed