FIELD: medicine, biochemistry.
SUBSTANCE: invention proposes applying CDP-choline (cytidinediphosphocholine) or its salt as a prophylactic agent for treatment of cerebral ischemia and a method for such prophylactic treatment. Invention found new and unknown early mechanism of action of CDP-choline or its salt: inhibition of activation of caspase cascade being the effectiveness of this effect is high in prophylactic intake of drug.
EFFECT: valuable medicinal properties of agent.
6 cl, 5 dwg, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| CDP-CHOLINE BEING THE PREPARATION FOR TREATING ALCOHOLIC ABSTINENCE SYNDROME AND THERAPEUTIC METHOD DUE TO ITS APPLICATION | 2001 |
|
RU2251422C2 |
| APPLICATION OF BETA-HYDROXYBUTYRATE OR ITS PHARMACEUTICALLY ACCEPTABLE SALTS FOR PREPARATION OF MEDICATION WHICH POSSESSES CYTOPROTECTIVE ACTIVITY, INCLUDING NEUROPROTECTIVE, CARDIOPROTECTIVE, ANTI-ISCHEMIC, ANTI-HYPOXIC, ANTI-STRESS, ACTOPROTECTIVE AND ADAPTOGENIC ACTIVITY, MEDICATION AND METHOD OF PREVENTION, RELIEF AND TREATMENT BY MEANS OF SAID MEDICATION | 2009 |
|
RU2426535C2 |
| AGENT WITH ANTIAPOPTOTIC ACTIVITY | 2018 |
|
RU2685428C1 |
| INJECTION FORM OF PHARMACEUTICAL COMPOSITION (VERSIONS) FOR PREVENTING AND TREATING NEUROPATHIES AND METHOD FOR PREPARING IT | 2010 |
|
RU2448706C2 |
| EDARAVON COMBINATION FOR TREATING ISCHEMIC BRAIN INJURY | 2017 |
|
RU2693627C2 |
| NEUROPROTECTIVE ACTION OF SOLUBLE URSODEOXYCHOLIC ACID IN MODELS OF FOCAL ISCHEMIA | 2005 |
|
RU2428987C2 |
| PHARMACEUTICAL NEUROPROTECTIVE, ANTIOXIDANT, ANTIHYPOXIC, ANTIAPOPTOTIC AND MEMBRANE PROTECTIVE COMPOSITION AND METHOD OF TREATMENT | 2008 |
|
RU2385722C1 |
| METHOD FOR NEUROTRAUMA TREATMENT | 2012 |
|
RU2749191C2 |
| HYBRID PROTEIN IGF-1-LONG FOR TREATING STROKE, NUCLEIC ACID, VECTOR, CELL, PHARMACEUTICAL COMPOSITION, METHOD OF TREATMENT | 2018 |
|
RU2711111C1 |
| COMPOUNDS AND PHARMACEUTIC COMBINATIONS FOR TREATMENT OF NEURODEGENERATIVE AND ISCHEMIC BRAIN DISEASES | 2012 |
|
RU2569302C2 |
