PHARMACEUTICAL COMPOSITION ELICITING HEPATOPROTECTIVE EFFECT AND MEDICINAL AGENT Russian patent published in 2005 - IPC

Abstract RU 2257208 C1

FIELD: medicine, pharmacy.

SUBSTANCE: invention concerns a pharmaceutical composition eliciting hepatoprotective effect. The base of pharmaceutical composition comprises adducts of orotic acid with amino acids or amines as an active substance. The composition comprises effective amount of active substance and special additives in the following ratio of active substance and special additives, wt.-%: active substance, 0.05-40.0; special additives, 60.0-99.95. As special additives the composition comprises starch, mixture of vitamins, lactose, aerosil, talc, stearates, polyvinylpyrrolidone, solid confectionary fat, Tween-80, polyethylene glycol, glycerol, citric acid, benzoic acid, sodium benzoate, correcting dye-substances. Compositions are made as tablets, capsules, lozenges, suppositories, syrups. Also, invention proposes a medicinal agent comprising above said pharmaceutical composition. Invention provides high pharmaco-therapeutical effect with fitness period 2 years, not less.

EFFECT: improved and valuable pharmaceutical properties of composition.

9 cl, 6 tbl, 8 ex

Similar patents RU2257208C1

Title Year Author Number
PHARMACEUTICAL COMPOSITION SHOWING HEPATOPROTECTIVE EFFECT 1996
  • Skachilova Sof'Ja Jakovlevna[Ru]
  • Ermakova Galina Aleksandrovna[Ru]
  • Radkevich Ljudmila Aleksandrovna[Ru]
  • Ostapchuk Natalija Vladlenovna[Ru]
  • Korshunov Igor' Borisovich[Ru]
  • Sernov Lev Nikolaevich[Ru]
  • Tjuljaev Ivan Ivanovich[Ru]
  • Bykov Vladimir Aleksandrovich[Ru]
  • Zuev Anatolij Petrovich[Ru]
  • Demchenko Boris Isidorovich[Ru]
  • Ljan Pavel Maksimovich[Ru]
  • Bak Zu Tak[Kr]
  • Jun Gil Zu[Kr]
  • Pyn'Ko Nehla Ehmirovna[Ru]
RU2111747C1
AN AQUEOUS SOLUTION SHOWING HEPATOPROTECTIVE EFFECT 1996
  • Radkevich Ljudmila Aleksandrovna[Ru]
  • Ostapchuk Natalija Vladlenovna[Ru]
  • Skachilova Sof'Ja Jakovlevna[Ru]
  • Ermakova Galina Aleksandrovna[Ru]
  • Pyn'Ko Nehla Ehmirovna[Ru]
  • Bendikov Ehduard Aleksandrovich[Ru]
  • Sernov Lev Nikolaevich[Ru]
  • Ljan Pavel Maksimovich[Ru]
  • Bak Zu Tak[Kr]
  • Jun Gil Zu[Kr]
RU2111746C1
ADDUCTS OF OROTIC ACID WITH AMINO ACIDS OR AMINES SHOWING HEPATOPROTECTIVE EFFECT 1993
  • Burov Ju.V.
  • Radkevich L.A.
  • Pleshakov M.G.
  • Snegotskij V.I.
  • Shamshina E.N.
  • Ostapchuk N.V.
  • Pyn'Ko N.Eh.
RU2047606C1
METHOD FOR PRODUCTION OF SIBERIAN CEDAR SEEDS LIQUEUR AND HEPATOPROTECTIVE PREPARATION PRODUCED BY SUCH METHOD 2014
  • Gorbatova Viktorija Viktorovna
RU2545700C1
ANTIOXIDANT AND MEMBRANE STABILISING AGENT 2012
  • L'Vovich Jakov Nakhmanovich
RU2540466C2
"CORSILIN" AS HEPATOPROTECTIVE PRODUCT 2002
  • Zharov O.V.
  • Novikov S.V.
  • Ustinova T.A.
  • Petukhova E.A.
  • Varjushina T.G.
RU2205637C1
HEPATOPROTECTIVE AND ANTIHEPATOTOXIC PHARMACEUTICAL COMPOSITION AND METHOD OF TREATING HEPATIC DISEASES THAT INVOLVES INTRODUCTION OF SAID COMPOSITION 2008
  • Kozhoka Timofej Georgievich
  • Jasinskij Sergej Jaroslavovich
RU2381800C1
USE OF PEGYLATED RECOMBINANT CHIMERIC MOUSE FIBROBLAST-21 GROWTH FACTOR OR ITS PHARMACEUTICALLY ACCEPTABLE SALT IN COMPOSITION OF DRUGS FOR TREATMENT OF NON-ALCOHOLIC STEATOHEPATITIS 2018
  • Li, Jian
  • Han, Jun
  • Ma, Xiaohui
  • Tai, Ping
  • Wang, Genbei
  • Cao, Xiaodan
  • Huang, Ruijing
  • Jin, Yongjie
  • Li, Jing
  • Chen, Chen
  • Jia, Guoyong
  • Wang, Yuanyuan
RU2785582C2
INJECTION DRUG FORM FOR TREATMENT AND PREVENTION OF LIVER DISEASES IN ANIMALS 2012
  • Staroverov Sergej Aleksandrovich
  • Volkov Aleksej Anatol'Evich
  • Engashev Sergej Vladimirovich
  • Kozlov Sergej Vasil'Evich
RU2504347C1
2-ETHYL-6-METHYL-3-HYDROXYLIRIDINIUMHYDROXYBUTANEDIOAT EXPRESSING ANTI-ISHEMIC, CEREBROPROTECTIVE, NEUROTROPIC AND LIPID-REGULATING ACTIVITY, PHARMACEUTICAL COMPOSITIONS AND MEDICAL PRODUCT 2008
  • Sernov Lev Nikolaevich
  • Kesarev Oleg Georgievich
  • Skachilova Sofija Jakovlevna
  • Mitrokhin Nikolaj Mikhajlovich
  • Aleshina Valentina Andreevna
  • Kesareva Zinaida Aleksandrovna
  • Zheltukhin Nikolaj Konstantinovich
RU2377237C1

RU 2 257 208 C1

Authors

Pleshakov M.G.

Snegotskij V.I.

Radkevich L.A.

Ostapchuk N.V.

Sernov L.N.

Dates

2005-07-27Published

2003-11-12Filed