METHOD FOR PREDICTING LINGERING CLINICAL COURSE OF VIRAL HEPATITIS IN CHILDREN Russian patent published in 2005 - IPC

FIELD: medicine.

SUBSTANCE: method involves studying properties of deformability DP, erythrocytes aggregation EA, lipids micro-viscosity LMV in their membranes, changes in superficial erythrocyte cytoarchitectonics on diskocytes and degenerative prehemolytic forms number and, additionally, extrahepatic vascular marks. The properties under study are evaluated by means of forecasting coefficients FK, where FK=+5.2, if DP≤0.11 conditional units; FK=-3.5, if DP≥0.12 conditional units; if EA≤1.11 conditional units, FK=+1.0; if EA≥1.12 conditional units, FK=-5.6; if LMV≥4.5 conditional units, FK=+2.3; LMV≤4.4 conditional units, FK=-6.5; the number of diskocytes falling to 70% and lower, FK=+4.1; diskocytes value being ≥71%, FK=-2.6; irreversibly transformed prehemolytic forms number being IRPF≥13%, FK=+2.9; IRPF≤12%, FK=-2.0; increasing reversibly transformed erythrocytes number being RTE≥14%, FK=+2.5; RTE≤13%, FK=-2.3; extrahepatic vascular marks being observed during acute viral hepatitis period, FK=+8.8, no extrahepatic vascular marks being observed, FK=-5.0. The forecasting coefficients are summed up. The sum of FK≥+13, lingering clinical viral hepatitis course is to be predicted.

EFFECT: high accuracy of the method.

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