METHOD FOR IDENTIFYING ANTI-ITCHING EFFECT OF ANTIDEPRESSANT Russian patent published in 2005 - IPC

Abstract RU 2266538 C2

FIELD: medicine, clinical pharmacology.

SUBSTANCE: invention relates to a method for identification of antidepressant possessing an anti-itching effect by using the computer program for measurement of models of chemical structures. Method involves visual analysis of all stable conformers of antidepressant molecule and antidepressant possessing anti-itching effect is identified in detection at least one stable conformer comprising structure of two inter-centered aromatic rings wherein their planes are able to orient at angle 120° with respect to one another. Also, invention relates to using antidepressant identified by above described method in treatment of itching. Invention provides identifying anti-itching effect of antidepressants.

EFFECT: improved method for identification.

2 cl, 7 ex

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RU 2 266 538 C2

Authors

Vanchakova N.P.

Shestakova N.N.

Rybakova K.V.

Dates

2005-12-20Published

2003-08-27Filed