O-ARYLGLUCOSIDE INHIBITORS OF SGLT2 AND METHOD FOR THEIR USING Russian patent published in 2006 - IPC C07H15/203 C07H15/26 A61K31/7034 A61P3/10 

Abstract RU 2269540 C2

FIELD: organic chemistry, biochemistry, medicine, endocrinology.

SUBSTANCE: invention relates to O-arylglucoside inhibitors of SGLT2 of the formula (I): wherein Y means compounds of formulae: A means -O(CH2)m, sulfur atom (S), -NH(CH2)m or -(CH2)n wherein n = 0-3; m = 0-2; R1-R6 are determined above, and to a pharmaceutical composition based on thereof, and to methods for treatment of diabetes mellitus type 2, and micro- and macrovascular diabetic complications.

EFFECT: valuable medicinal properties of inhibitors.

15 cl, 1 tbl, 99 ex

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RU 2 269 540 C2

Authors

Uoshbarn Uil'Jam N.

Sher Filip M.

Vu Gang

Dates

2006-02-10Published

2001-03-29Filed