FIELD: organic chemistry, biochemistry, medicine, endocrinology.
SUBSTANCE: invention relates to O-arylglucoside inhibitors of SGLT2 of the formula (I): wherein Y means compounds of formulae: A means -O(CH2)m, sulfur atom (S), -NH(CH2)m or -(CH2)n wherein n = 0-3; m = 0-2; R1-R6 are determined above, and to a pharmaceutical composition based on thereof, and to methods for treatment of diabetes mellitus type 2, and micro- and macrovascular diabetic complications.
EFFECT: valuable medicinal properties of inhibitors.
15 cl, 1 tbl, 99 ex
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Authors
Dates
2006-02-10—Published
2001-03-29—Filed