RECOMBINANT MODIFIED VIRUS OF VACCINE ANKARA ABLE TO EXPRESS HEPATITIS C VIRUS STRUCTURAL ANTIGENS Russian patent published in 2006 - IPC C12N7/01 C12N15/39 C12N15/51 C12N5/10 A61K39/29 A61P31/14

Abstract RU 2270860 C2

FIELD: genetic engineering, virology, pharmacy.

SUBSTANCE: invention proposes the recombinant modified virus OF VACCINE Ankara able to express structural antigens of hepatitis C virus. Virus comprises DNA sequences encoding structural antigens of hepatitis C virus or their functional regions or epitopes of hepatitis C virus structural antigens. Also, invention proposes a pharmaceutical composition comprising such virus, eucaryotic cell infected with such virus, a method for preparing such virus and a method for preparing hepatitis C virus structural polypeptides. Invention can be used in virology and medicine for preparing hepatitis C virus antigen.

EFFECT: valuable properties of virus.

20 cl, 14 dwg, 1 tbl

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RU 2 270 860 C2

Authors

Zutter Gerd

Ehrfle Volker

Shtajb Karolin

Van Juan'

Li Guandi

Chzhu Lisin'

Dates

2006-02-27—Published

2002-09-05—Filed