USING RECEPTOR AT-1 ANTAGONIST OR RECEPTOR AT-2 MODULATOR IN TREATMENT OF DISEASES ASSOCIATED WITH INCREASE CONTENT OF AT-1 OR AT-2 RECEPTORS Russian patent published in 2006 - IPC A61K31/41 A61P35/00

Abstract RU 2271809 C2

FIELD: medicine, oncology.

SUBSTANCE: invention proposes using a medicine valsartan as an antagonist of AT-1 receptors and a modulator of AT-2 receptors in treatment of lung or mammary glands invasive cancer. All carcinomas comprise AT-2 receptors while in hyperplasia of normal epithelial cells AT-2 receptors are localized only. This allows carrying out both diagnosis of malignant tumor development and treatment indicated diseases with valsartan owing to modulation of AT-2 receptors, i. e. based on change of the host biological response for tumor cells.

EFFECT: improved and valuable medicinal properties of medicine agent.

13 tbl, 12 ex

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RU 2 271 809 C2

Authors

Ballok Dzhillian Rouzmari

De-Gasparo Mark

Ganter Zabina Marija

Dates

2006-03-20—Published

1999-12-22—Filed