NEW COMPOSITIONS AND METHODS FOR THEIR STABILIZATION Russian patent published in 2006 - IPC C07D311/94 C07D333/78 C07D221/04 A61K31/352 A61K31/382 A61K31/435 A61P11/00 

FIELD: organic chemistry, pharmacy.

SUBSTANCE: invention relates to new pharmaceutical compositions comprising bicyclic compound of the formula (I): wherein A means -COOH or their functional derivative; X₁ and X₂ mean hydrogen or halogen atom; V₁ and V₂ mean carbon atoms; W₁ and W₂ mean groups and wherein R₄ and R mean hydrogen atom, hydroxy-group; Z means carbon, oxygen, sulfur or nitrogen atom; R₁ means saturated or unsaturated bivalent (C₁-C₁₀)-aliphatic hydrocarbon residue; R₂ means saturated or unsaturated (C₁-C₁₀)-aliphatic hydrocarbon residue; R₃ means hydrogen atom and glyceride. Also, invention relates to a method for stabilizing compositions and novel bicyclic compounds. Invention provides enhancing stability of pharmaceutical composition based on its dissolving in glyceride.

EFFECT: improved and valuable properties of compositions, improved stabilization of compositions.

42 cl, 8 tbl, 8 ex