DERIVATIVES OF DIPHENYLAZETHIDINONE, MEDICINAL AGENTS COMPRISING THESE COMPOUNDS AND THEIR USING Russian patent published in 2006 - IPC C07D409/12 A61K31/397 A61P3/10 

Abstract RU 2275370 C2

FIELD: organic chemistry, medicine, pharmacy.

SUBSTANCE: invention relates to derivatives of diphenylazathedinone of the general formula (I): wherein R1, R2, R3 and R4 mean independently of one another (0-C30)-alkylene-L wherein one or some C-atoms of alkylene residue can be substituted with -O-, -(C=O)- or -NH- and, except for, R1-R6 can represent hydrogen atom (H), fluorine atom (F), and L represents compound of the formula: , and their pharmaceutically tolerated salts also. Compounds of the formula (I) elicit hypolipidemic effect and can be used in therapeutic aims. Also, invention describes a medicinal agent and its using.

EFFECT: valuable medicinal properties of compounds.

7 cl, 31 ex

Similar patents RU2275370C2

Title Year Author Number
ORTHO-SUBSTITUTED DERIVATIVES OF BENZOIC ACID, METHOD AND INTERMEDIATE COMPOUNDS FOR THEIR PREPARING, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND USING 2003
  • Li Lanna
RU2288912C2
CARBOXAMIDE COMPOUNDS AND USE THEREOF AS CALPAIN INHIBITORS 2010
  • Kling Andreas
  • Jantos Katja
  • Mak Khel'Mut
  • Meller Akhim
  • Khornberger Vil'Frid
  • Bakfish Gizela
  • Lao Jan'Bin'
  • Nejsen Mar'Olen
RU2567392C2
NOVEL 1,2-DIPHENYLAZEAZETHIDINONES, THEIR USING IN TREATMENT OF LIPID METABOLISM DISORDER, MEDICINAL AGENT AND METHOD FOR ITS PREPARING 2001
  • Glombik Khajner
  • Kramer Verner
  • Flor Shtefani
  • Frik Vendelin
  • Khojer Khubert
  • Jene Gerkhard
  • Lindenshmidt Andreas
  • Shefer Khans-Ljudvig
RU2286985C2
THIENO[2,3-c]QUINOLIN-4-ONE DERIVATIVES, USEFUL IN TREATMENT OF ERK-DEPENDENT DISEASE 2011
  • Nakamura Jusuke
  • Matsuo E
  • Khisada Sodzi
  • Akhmed Fer'Jan
  • Khantli Rehjmond
  • Sadzhdzhadi-Khashemi Zokhrekh
  • Dzhenkins Dehvid M.
  • Kargbo Robert B.
  • Tsuj Vehneh
  • Gouan Polivina Kholisija F.
  • Uolker Dzhoehl R.
  • Dekorne Ehlen
  • Gurram Makhender
RU2574398C2
BENZOTHIADIAZEPINE DERIVATIVES AND METHOD FOR PRODUCTION THEREOF (VARIANTS) 2002
  • Starke Ingemar
  • Dal'Strum Mikaehl' Ul'F Jukhan
  • Blumberg David
  • Alenfal'K Suzanne
  • Sharet Ture
  • Lemurell' Malin
RU2305681C2
DERIVATIVES OF SUBSTITUTED PHENYLPROPIONIC ACID AS AGONISTS OF HUMAN ALPHA-RECEPTORS ACTIVATED BY PEROXISOME PROLIFERATOR (PPARα), METHOD AND INTERMEDIATE COMPOUNDS FOR THEIR PREPARING, PHARMACEUTICAL COMPOSITION BASED ON THEREOF, THEIR USING AND METHODS FOR TREATMENT OF DYSLIPIDEMIA IN DIABETES MELLITUS TYPE 2 2002
  • Al'Stermark Lindstedt Ehva-Lotte
  • Ol'Sson Anna Kristina
  • Li Lanna
RU2303031C2
1,5-BENZOTHIAZEPINES AND EMPLOYMENT THEREOF AS ANTIHYPERLIPIDEMIC DRUGS 2001
  • Starke Ingemar
  • Dal'Strom Mikaehl'
  • Blomberg David
RU2302414C2
DERIVATIVES OF SUBSTITUTED PHENYLPROPIONIC ACID AS AGONISTS OF HUMAN ALPHA-RECEPTOR (PPARα) ACTIVATED BY PEROXISOME PROLIFERATORS, METHOD AND INTERMEDIATE COMPOUNDS FOR THEIR PREPARING, PHARMACEUTICAL COMPOSITION BASED ON THEREOF, THEIR USING AND METHODS FOR DYSLIPIDEMIA TREATMENT AND TYPE 2 DIABETES MELLITUS 2002
  • Al'Stermark Lindstedt Ehva-Lotte
  • Ol'Sson Anna Kristina
  • Li Lanna
RU2300517C2
NOVEL COMPOUNDS OF SUBSTITUTED N-(3-FLUOROPROPYL)PYRROLIDINE, METHODS FOR PRODUCTION THEREOF AND THERAPEUTIC APPLICATION THEREOF 2017
  • Bouaboula, Monsif
  • Brollo, Maurice
  • Certal, Victor
  • El-Ahmad, Youssef
  • Filoche-Romme, Bruno
  • Halley, Frank
  • Mccort, Gary
  • Schio, Laurent
  • Tabart, Michel
  • Terrier, Corinne
  • Thompson, Fabienne
RU2742278C2
TETRAHYDROPYRIDINE DERIVATIVES AND USE THEREOF AS ANTIBACTERIAL AGENTS 2017
  • Choi, Sun-Ho
  • Im, Weon-Bin
  • Choi, Sung-Hak
  • Cho, Chong-Hwan
  • Moon, Ho-Sang
  • Park, Jung-Sang
  • Lee, Min-Jung
  • Sung, Hyun-Jung
  • Moon, Jun-Hwan
  • Song, Seung-Hyun
  • Lee, Hyung-Keun
  • Choi, Ji-Hoon
  • Park, Cheon-Hyoung
  • Kim, Yoon-Jung
  • Kim, Jin-Hyuk
RU2722594C1

RU 2 275 370 C2

Authors

Glombik Khajner

Kramer Verner

Flor Shtefani

Frik Vendelin

Khojer Khubert

Jene Gerkhard

Lindenshmidt Andreas

Shefer Khans-Ljudvig

Dates

2006-04-27Published

2001-12-11Filed