FIELD: organic chemistry, medicine.
SUBSTANCE: invention relates to benzothiadiazepine derivatives of general formula I 
wherein M represents -N-one of R4 and R5 representsgroum of formula 
ring A represents aryl; or hydrolysable in vivo pharmaceutically acceptable salts, esters and amides thereof. Such derivatives are useful as inhibitors of bile acid transfer in ileal intestine (IBAT) for hyperlipemia treatment. Methods for production of abovementioned derivatives also are described.
EFFECT: new benzothiadiazepine derivatives for hyperlipemia treatment.
14 cl, 67 ex
| Title |
Year |
Author |
Number |
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|
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