FIELD: medicine, virology, pharmacology.
SUBSTANCE: invention relates to an antiviral substance based on hemolymph of insects of subclass Pterigota. This substance is prepared by activation of immune system of insects, collection of hemolymph and the following treatment of prepared hemolymph by centrifugation, chromatography of supernatant, elution of hydrophobic components sobbed on column. Prepared eluate comprises a mixture of hydrophobic components possessing with an antiviral activity. Invention provides the direct antiviral effect and enhances resistance of body cells to viral infection by virus disruption or blocking its replication, or by other method.
EFFECT: improved preparing method, valuable antiviral properties of substance.
41 cl, 1 tbl, 1 dwg, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| ANTIMICROBIAL AGENT | 2010 |
|
RU2447896C1 |
| METHOD OF DESTROYING AND PREVENTING FORMATION OF BACTERIAL BIOFILMS BY COMPLEX OF ANTIMICROBIAL PEPTIDES OF INSECTS | 2017 |
|
RU2664708C1 |
| METHOD FOR SCREENING USING INSECTS WITH BLOOD-BRAIN BARRIER | 2009 |
|
RU2503004C2 |
| AGENT FOR EXTERNAL APPLICATION, POSSESSING ANTIVIRAL ACTIVITY | 2006 |
|
RU2338553C2 |
| COCKROACH CONTROL METHOD | 0 |
|
SU1743330A3 |
| METHOD OF POTENTIATION OF PESTICIDE ACTIVITY OF PESTICIDE OBTAINED ON BASIS OF MICROORGANISMS OF GENUS BACILLUS | 1996 |
|
RU2192744C2 |
| AXM1554 GENE ENCODING DELTA-ENDOTOXIN AND METHODS FOR ITS APPLICATION | 2016 |
|
RU2755282C2 |
| ANTI-TUMOR AND ANTIVIRAL PEPTIDES | 2004 |
|
RU2267496C2 |
| METHOD OF OBTAINING OF COMPLEX OF ANTIMICROBIC PEPTIDES OF INSECT | 2013 |
|
RU2552157C1 |
| ALLOPHERONES AS IMMUNOMODULATING PEPTIDES | 1999 |
|
RU2172322C1 |
