VINORELBIN-CONTAINING ORAL PHARMACEUTICAL COMPOSITION FOR SOFT CAPSULE AND METHOD FOR TREATMENT Russian patent published in 2006 - IPC A61K9/48 A61K31/475 A61P35/00 

Abstract RU 2279873 C2

FIELD: medicine, oncology, pharmacy.

SUBSTANCE: invention describes a liquid pharmaceutical composition used in treatment of cancer and comprising vinorelbin as an active component and is useful for incapsulation into soft capsules. The liquid oral pharmaceutical composition useful as a liquid filling agent composition for the dosed formulation as a soft capsule comprises vinorelbin or its pharmaceutically acceptable salt, in particular, vinorelbin tartrate, ethanol, water, glycerol and polyethylene glycol. Also, invention relates to a method for preparing cancer that involves oral administration to a patient a soft capsule comprising the pharmaceutical composition. The liquid composition containing vinorelbin proves the improved solubility and bioavailability for oral administration.

EFFECT: improved and valuable pharmaceutical and medicinal properties of pharmaceutical composition.

13 cl, 7 tbl, 6 ex

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RU 2 279 873 C2

Authors

Bugare Zhoehl'

Lever Ehli

Bon Mari-Madlen

Khajntts Norbert

Dates

2006-07-20Published

2003-05-28Filed