BEE VENUM ALLERGOID FOR ALLERGEN-SPECIFIC THERAPY OF PATIENTS WITH ALLERGIC RESPONSE FOR BEE STINGING AND METHOD FOR ITS PREPARING Russian patent published in 2006 - IPC A61K35/64 A61P37/08 

FIELD: medicine, allergology, chemical-pharmaceutical industry.

SUBSTANCE: invention proposes an allergoid for carrying out the allergen-specific immunotherapy of patients with allergic responses for stinging by bees that comprises allergen fraction of molecular mass 3-12; 16-31; 38-46; 20 and 60 kDa. Allergoid is prepared by polymerization of the total allergen fraction with formaldehyde and by stabilization with NaBH₄. Also, invention proposes a method for preparing allergoid and a method for carrying out the allergen-specific immunotherapy of patients with allergic response for stinging by bees by using the proposed allergen. Invention provides preparing allergoid showing high specific activity and safety in using.

EFFECT: improved preparing method, valuable medicinal properties of allergoid.

5 cl, 2 tbl