FIELD: organic chemistry, medicine, biochemistry, pharmacy, chemical-pharmaceutical industry.
SUBSTANCE: invention relates to derivatives of aminodicarboxylic acids of the general formula (I) and a medicinal agent able to stimulate activity of soluble guanylate cyclase being independently of the presence of the heme group comprising in it and able to cause relaxation of vessels and comprising at least one compound of the general formula (I). Agent is designated for treatment of cardiovascular diseases and for treatment of the central nervous system diseases characterizing by disorder of the system NO/cGMP, and shows high bioavailability and effectiveness.
EFFECT: improved and valuable medicinal properties of agent.
7 cl, 232 ex
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Authors
Dates
2006-07-20—Published
2000-08-31—Filed