NEW DERIVATIVES OF AMINODICARBOXYLIC ACIDS POSSESSING PHARMACEUTICAL PROPERTIES Russian patent published in 2006 - IPC C07C219/28 C07C229/38 C07C237/12 C07D239/30 C07D277/56 C07D271/06 C07D285/06 C07D239/38 C07D333/16 C07D263/57 C07D333/56 A61K31/24 A61K31/197 A61K31/165 A61K31/505 A61K31/426 A61K31/4245 A61K31/433 A61K31/381 A61P9/00 

Abstract RU 2280025 C9

FIELD: organic chemistry, medicine, biochemistry, pharmacy, chemical-pharmaceutical industry.

SUBSTANCE: invention relates to derivatives of aminodicarboxylic acids of the general formula (I) and a medicinal agent able to stimulate activity of soluble guanylate cyclase being independently of the presence of the heme group comprising in it and able to cause relaxation of vessels and comprising at least one compound of the general formula (I). Agent is designated for treatment of cardiovascular diseases and for treatment of the central nervous system diseases characterizing by disorder of the system NO/cGMP, and shows high bioavailability and effectiveness.

EFFECT: improved and valuable medicinal properties of agent.

7 cl, 232 ex

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RU 2 280 025 C9

Authors

Alonso-Alija Kristina

Khajl' Markus

Flubakher Ditmar

Naab Paul'

Pernershtorfer Jozef

Shtash Jokhannes-Peter

Vunder Frank

Dembovski Klaus

Pertsborn Ehlizabet

Shtal' Ehl'Ke

Dates

2006-07-20Published

2000-08-31Filed