FIELD: organic chemistry, pharmacology.
SUBSTANCE: invention relates to intermediate diketone of formula 
, wherein R1 is selected from -CHF2, -CF3, -CClF2CF3, -CF2CF2CF3; R1 is hydrogen or halogen; RQ is hydrogen, methyl or methoxy, provided that at least one from R1 and RP is not halogen when RQ is hydrogen.
EFFECT: intermediate for 3-halogene-1H-pyrasole synthesis having pharmacological activity, including hypoglycemic and anti-inflammatory activity.
7 cl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PREPARING 3-HALOGENALKYL-1H- PYRAZOLES | 1996 |
|
RU2169143C2 |
| SYNTHESIS OF DIARYLPYRAZOLES | 2003 |
|
RU2319695C2 |
| 2-CYCLOOXYGENASE INHIBITORS AS ANTIANGIOGENIC AGENTS | 1997 |
|
RU2268716C2 |
| METHOD FOR TREATING INFLAMMATION OR INFLAMMATION-INDUCED DISEASE IN DOGS | 1996 |
|
RU2253456C2 |
| PYRAZOLYL-SUBSTITUTED BENZENESULFONEAMIDE OR ITS PHARMACEUTICALLY ACCEPTABLE SALT, METHOD OF TREATMENT OF PATIENTS WITH INFLAMMATION OR INFLAMMATION-ASSOCIATED DISEASES | 1994 |
|
RU2139281C1 |
| COMBINED THERAPY INCLUDING SGLT INHIBITORS AND DPP4 INHIBITORS | 2009 |
|
RU2481106C2 |
| NOVEL PHENYLPYRAZINONES AS KINASE INHIBITORS | 2009 |
|
RU2507202C2 |
| OBTAINING SUBSTITUTED ACRYLATE COMPOUND | 2021 |
|
RU2830161C1 |
| METHOD OF PRODUCING PYRAZOLES | 2015 |
|
RU2712192C2 |
| QUINAZOLINE DERIVATIVES | 2004 |
|
RU2356896C2 |
