METHOD FOR PREDICTING BODY INTOXICATION WITH LEAD Russian patent published in 2006 - IPC A61B10/00 G01N33/48 

FIELD: medicine, diagnostics.

SUBSTANCE: due to spectrophotometry on should study body biological material to detect the concentration of porphyrin in tissues of biological material and compare it values against the standard. As biological material one should apply that part of the tissue at patient's body where spectrophotometric investigation should be carried out in vivo. Moreover, One should affect this part with low-intensity laser radiation, wave length corresponds to one of the maximums of protoporphyrins' absorption range. One should determine the amplitude of fluorescence radiation of this part. As a standard for comparison one should take the amplitude of fluorescence of protoporphyrin IX that models the concentration of protoporphyrin in blood erythrocytes ranged 100-1500 mcg/l and more. At equality of amplitudes it is necessary to establish concentration of proptoporphyrin IX in blood erythrocytes of biological tissue under testing. Moreover, wave lengths corresponding to maximums of absorption range of protoporphyrins correspond to 337, 370, 405, 532, 632 nm. The innovation enables to considerably simplify the investigation of values that indirectly characterize lead concentration in tissues and, thus, total degree lead intoxication in patients with the risk of lead intoxication.

EFFECT: higher efficiency of diagnostics.

1 cl, 1 ex