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IPC

G09B23/28(2006-01-01)

A61K31/138(2006-01-01)

A61P7/06(2006-01-01)

(21) (22)

Application

2005102549/14, 2005-02-02

(24)

Start date

2005-02-02

(22)

Actual filing date

2005-02-02

(45)

Published

2006-10-10

(72)

Inventor

Gol'Dberg Evgenij DanilovichDygaj Aleksandr MikhajlovichZjuz'Kov Gleb Nikolaevich

(73)

Holder

Gu Nauchno-Issledovatel'Skij Institut Farmakologii Tomskogo Nauchnogo Tsentra Sibirskogo Otdelenija Rossijskoj Akademii Meditsinskikh Nauk Farmakologii Tnts So Ran)

METHOD FOR CORRECTING AFFECTED ERYTHROPOIESIS AT EXPERIMENTAL HYPOXIA Russian patent published in 2006 - IPC G09B23/28 A61K31/138 A61P7/06

Abstract RU 2285300 C1

FIELD: medicine, pharmacology.

SUBSTANCE: the present innovation deals with correcting affected erythropoiesis in case of severe hypoxia. One should fulfill subcutaneous single injection of propranolol for laboratory mice on the 2^nd d after hypoxia modeling at the dosage of 5 mg/kg. The innovation enables to improve the dynamics for reconstructing cellularity and qualitative values of erythroid source of blood formation, increase the number of erythrocytes in peripheral blood at decreasing the production of their pathological forms due to preventing the lesion of commitment precursor cells of erythropoiesis in post-hypoxic period.

EFFECT: higher efficiency of correction.

3 ex, 3 tbl

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RU 2 285 300 C1

Authors

Gol'Dberg Evgenij Danilovich

Dygaj Aleksandr Mikhajlovich

Zjuz'Kov Gleb Nikolaevich

Dates

2006-10-10—Published

2005-02-02—Filed