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2 354 376

(13)

(51)

IPC

A61K31/451(2006-01-01)

A61P7/06(2006-01-01)

(21) (22)

Application

2007123856/15, 2007-06-25

(24)

Start date

2007-06-25

(22)

Actual filing date

2007-06-25

(45)

Published

2009-05-10

(72)

Inventor

Gol'Dberg Evgenij DanilovichDygaj Aleksandr MikhajlovichSkurikhin Evgenij GermanovichPershina Ol'Ga Viktorovna

(73)

Holder

Gosudarstvennoe Uchrezhdenie Nauchno-Issledovatel'Skij Institut Farmakologii Tomskogo Nauchnogo Tsentra Sibirskogo Otdelenija Rossijskoj Akademii Meditsinskikh Nauk Gu Nii Farmakologii Tnts So Ramn

PREPARATION PREVENTING DEVELOPMENT OF DEPRESSION OF ERITHROID HEMATOPOIESIS SHOOT WITH INTRODUCTION OF CYTOSTATIC Russian patent published in 2009 - IPC A61K31/451 A61P7/06

Abstract RU 2354376 C1

FIELD: pharmacology.

SUBSTANCE: claimed is preparation for pharmacological correction of erythropoiesis disturbances, developing under cytostatic influence, - cyproheptadine. Said antiserotin preparation was introduced 30 minutes before cytostatic 5-fluoruracyl. This resulted in formation of additional areas of erytyhroid and mixed hematopoiesis.

EFFECT: cyproheptadine increased number of eryth-rocariocytes in bone marrow and reticulocytes in peripheral blood.

5 tbl, 1 ex

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RU 2 354 376 C1

Authors

Gol'Dberg Evgenij Danilovich

Dygaj Aleksandr Mikhajlovich

Skurikhin Evgenij Germanovich

Pershina Ol'Ga Viktorovna

Dates

2009-05-10—Published

2007-06-25—Filed