FIELD: medicine.
SUBSTANCE: medication represents neuroleptic galoperidol. Claimed invention solves the task of extending arsenal of medications used for preventing development of hematopoiesis erythroid lineage depression, which develops at the background of cytostatics apdministration. Galoperidol, when introduced 30 min before cyclophosphan, prevented depression of bone marrow erythropoiesis, caused increase of number of erythrocytes in bone marrow and reticulocytes in peripheral blood. Galoperidol caused formation of additional hematopoiesis sites of erythrocyte and mixed hematopoiesis and change of production of erythropoietic activity of adhesing cell elements of hemopoiesis-inducing micro-environment.
EFFECT: pharmacologic correction of disturbances of blood system developing under cytostatic influence.
5 tbl
| Title | Year | Author | Number |
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| TREATMENT METHOD FOR HEMATOPOIETIC ERYTHROID LINEAGE DEPRESSION IN CYTOSTATIC MYELOSUPRESSION | 2008 |
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| METHOD OF GRANULOCYTOPOIESIS DEPRESSION CORRECTION IN CYTOSTATIC ACTION | 2008 |
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| MEDICINAL AGENT STIMULATING ERYTHROIDE HEMOPOIESIS GERM AT CYTOSTATIC MYELODEPRESSION STATES | 1992 |
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| PREPARATION PREVENTING DEVELOPMENT OF DEPRESSION OF ERITHROID HEMATOPOIESIS SHOOT WITH INTRODUCTION OF CYTOSTATIC | 2007 |
|
RU2354376C1 |
| METHOD OF DETERMINING EFFICACY OF HAEMOSTIMULATORS IN CYTOSTATIC MYELOSUPPRESSION | 2009 |
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| MEDICINAL AGENT STIMULATING ERYTHROID AND GRANULOCYTE ERYTHROPOIESIS STEMS AT CYTOSTATIC MYELODEPRESSIONS | 1993 |
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| METHOD OF MYELOPOIESIS STIMULATION | 2007 |
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RU2336899C1 |
| METHOD OF MYELOPOIESIS STIMULATION | 2008 |
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RU2366452C1 |
| ANTIMUTAGENIC AGENT | 2000 |
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RU2189232C2 |
| AGENT STIMULATING ERYTHROIDAL AND GRANULOCYTIC HEMOPOIESIS STEMS IN CYTOSTATIC MYELODEPRESSION | 2003 |
|
RU2243782C1 |
