METHOD FOR TREATMENT OF AIDS Russian patent published in 2006 - IPC A61K31/495 A61K35/14 A61K39/12 A61P31/18 A61M1/36 

Abstract RU 2285529 C2

FIELD: medicine, infectious diseases.

SUBSTANCE: method involves carrying out the step-by-step treatment wherein the following agents are administrated at the first step in turn: inhibitor and activator of virus replication; hemosorption is carried out at the second step; reablement of immune system is carried out at the third step by using blood enriched with stem cells, and specific immunostimulation. Hemosorption is carried out by using columns wherein each comprises a matrix with agarose-immobilized ligands comprising, respectively: the first - specific antiviral antibodies, the second - CD4-receptors, the third - receptors raised to gamma-interferon, the fourth - receptors raised to Fc-fragment of immunoglobulin G, the fifth - antimicrobial proteins of mammalian origin, and blood enriched with stem cells is administrated by intravenous route. Invention promotes to the maximal sorption of HIV and its elimination, limiting the iatrogenic immunosuppression that, in turn, promotes to reducing risk for virus persistence in the patient body. Invention can be used in treatment of patients with AIDS.

EFFECT: enhanced effectiveness of treatment.

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RU 2 285 529 C2

Authors

Lobzin Jurij Vladimirovich

Aleksandrov Viktor Nikolaevich

Makeev Boris Lavrovich

Dates

2006-10-20Published

2004-07-16Filed