COMPOSITION COMPRISING LOW-MOLECULAR FRAGMENTS OF PEPTIDOGLICANE OF GRAM-NEGATIVE BACTERIA FOR PREVENTING OR TREATING OF HUMAN DISEASES Russian patent published in 2012 - IPC C12N1/00 

Abstract RU 2441906 C2

FIELD: pharmacology.

SUBSTANCE: invention relates to the area of biotechnology. The pharmaceutical composition comprising three components of bacterial nature are described: (1) beta-N-acetyl-D-glucosaminyl-(1-4)-N-acetyl-D-muramoyl-L-alanine-D-isoglutaminyl-meso-diaminopimyelinic acid (GMtri), (2) beta-N-acetyl-D-glucosaminyl-(1-4)-N-acetyl-D-muramoyl-L-alanine-D-isoglutaminyl-meso-diaminopimyeloid-D-alanine (GMtetra), (3) GMtetra dimer (di-GMtetra) in which tetrameric residues of GMtetra are held together by an amide bond between carboxyl group of terminal D-alanine of one residue and w-amino group of meso-diaminopimyelinic acid of the other. The composition is proposed for obtaining a medicinal product for preventing or treating of diseases and conditions caused by bacteria that require enhancing nonspecific resistance of the organism to bacteria, diseases caused by Human Immuno-deficiency Virus (HIV) and herpes simplex virus, or diseases and conditions that require the organism's properties of malignant tumor rejection or myelopoiesis stimulation. A set for preventing or treating of diseases and conditions that comprses the above composition in a dosage form is disclosed, too.

EFFECT: increased effectiveness of certain medicines.

16 cl, 8 tbl

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RU 2 441 906 C2

Authors

L'Vov Vjacheslav Leonidovich

Pinegin Boris Vladimirovich

Khaitov Rakhim Musaevich

Pashchenkov Mikhail Vladimirovich

Dates

2012-02-10Published

2009-07-24Filed