APPLICATION OF SINGLE DOSE OF CD20-SPECIFIC BINDING MOLECULES Russian patent published in 2011 - IPC A61K39/395 A61P37/00 A61P19/02 A61P35/00 

Abstract RU 2421242 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to medicine, namely to arthrology, rheumatology, and can be used for treating rheumatoid arthritis. That is ensured by introducing human CD20 specific small modular immune-pharmaceutical (SMIP) protein in a therapeutically effective amount to the patient. The introduction is single, and the supporting treatment is not performed for approximately three months to two years after the introduction of a first single dose.

EFFECT: single introduction provides almost complete B-cell elimination and considerable prolonged rheumatoid factor level reduction in said category of patients.

24 cl, 4 tbl, 8 ex, 5 dwg

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RU 2 421 242 C2

Authors

Berdzh Dehniel Dzhonatan

Dates

2011-06-20Published

2006-07-25Filed