FIELD: medicine, pharmaceuticals, in particular compositions for treatment of insulin-independent II type diabetus mellitus.
SUBSTANCE: claimed composition represents single solid dosed pharmaceutical for oral administration and contains effective dose of metformin and glibenclamide, wherein said glibenclamide contains powdery particles with specific surface of 1.7-2.2 m2/g. Also disclosed are method for treatment of insulin-independent diabetes or hyperglycemia; method for providing and enhancing of glibenclamide bioavailability in human body (variants).
EFFECT: composition with increased glibenclamide bioavailability.
68 cl, 3 ex, 7 tbl, 3 dwg
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