FIELD: medicine, pharmaceutics.
SUBSTANCE: pharmaceutical composition of prolonged release in form of pill includes metformin or its pharmaceutically acceptable salt; agent, which generates gas, selected from carbonates or bicarbonates; hydrophilic or hydrophobic polymer as release moderator; disintegration-causing agent; hydrophilic polymer for ensuring system stability; additional hydrophilic polymer or gum as release moderator, binding substance and other pharmaceutical additional substances.
EFFECT: composition by invention ensures increased term of device holding in stomach and release of metformin by regulated method, in addition, it is simple and cheap in production.
19 cl, 1 dwg, 11 tbl, 8 ex
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