ANTIBACTERIAL FILLER FOR FEMALE ABSORBENT ARTICLES, METHOD FOR PRODUCTION AND USES THEREOF Russian patent published in 2006 - IPC A61L15/28 A61L15/44 A61K31/498 A61K31/4164 A61K31/722 A61P31/04 

Abstract RU 2286800 C1

FIELD: medicine, in particular gynecology.

SUBSTANCE: claimed filler contains 1 % hydrogel of chitosan with molecular mass of 300-700 kDa and deacetylation ratio of at least 89 %, as well as metronidazole and dioxydine; and 1 l of composition contains (g): dry chitosan chlorohydrate 10; metronidazole 1.250-1.665; dioxydine 2.5; and balance: distilled water. Method for filler production includes stirring of 10 g dry chitosan chlorohydrate in 300 ml of distilled water heated up to 50°C for 20-30 min until full dissolution. Then gradually under intense agitation 250-333 ml of metronidazole for intravenous injection is added, mixture is thoroughly stirred for 5 min, further gradually under intense agitation 250 ml of 1% dioxydine solution is added, mixture is thoroughly stirred for 10 min and packed in container made of dark glass or plastics for storage. Methods for treatment of female genitals diseases by using absorbent articles containing filler of present invention also are disclosed.

EFFECT: non-toxic filler with prolonged antiinflammation and antibacterial effects.

3 cl, 3 tbl

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RU 2 286 800 C1

Authors

Bol'Shakov Igor' Nikolaevich

Per'Janova Ol'Ga Vladimirovna

Stepanova Anastasija Ivanovna

Poljanskaja Rimma Timofeevna

Barkova Anna Jur'Evna

Fadeeva Elena Konstantinovna

Ruppel' Nadezhda Ivanovna

Dates

2006-11-10Published

2005-05-11Filed