NEUROTROPIC TACROLIMUS ANALOGS Russian patent published in 2006 - IPC A61K31/436 A61P25/00 A61P25/28 

Abstract RU 2288716 C2

FIELD: medicine.

SUBSTANCE: method involves introducing tacrolimus derivative of known formula (1) for stimulating nerve cell growth or regeneration. Another method is suggested for repairing transected peripheral nerve or spinal cord by making contact of the transected peripheral nerve ends or spinal cord with the compound (1) or by introduced the compound (1) to the patient and transplanting a transplant into peripheral nerve or spinal cord.

EFFECT: sharp growth of regenerated myelinated axons; improved motor function of feet; high neurotropic and low immunosuppressive activity level.

17 cl, 8 tbl

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RU 2 288 716 C2

Authors

Matsuoka Nobuja

Jamadzi Takajuki

Gold Brjus

Dates

2006-12-10Published

2001-12-31Filed