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2 288 733

(13)

(51)

IPC

A61K36/41(2006-01-01)

A61K31/351(2006-01-01)

A61K125/00(2006-01-01)

A61P25/28(2006-01-01)

(21) (22)

Application

2005125170/15, 2005-08-08

(24)

Start date

2005-08-08

(22)

Actual filing date

2005-08-08

(45)

Published

2006-12-10

(72)

Inventor

Kurkin Vladimir AleksandrovichDubishchev Aleksej VladimirovichEzhkov Vladimir NikolaevichTitova Irina Nikolaevna

(73)

Holder

Kurkin Vladimir AleksandrovichDubishchev Aleksej VladimirovichEzhkov Vladimir NikolaevichTitova Irina Nikolaevna

METHOD FOR PREPARING SUBSTANCE POSSESSING NOOTROPIC ACTIVITY Russian patent published in 2006 - IPC A61K36/41 A61K31/351 A61K125/00 A61P25/28

Abstract RU 2288733 C1

FIELD: medicine, pharmaceutical industry, pharmacy.

SUBSTANCE: invention relates to a method for preparing rosavine possessing the nootropic activity. Method for preparing rosavine involves three-fold extraction of rosewort (Rhodiola rosea L.) milled rhizomes with 70-90% ethyl alcohol in the definite ratio raw : extractant, evaporation of combined extracts under vacuum to obtain dense residue, chromatography separation on silica gel, evaporation of eluates and crystallization wherein the first extraction is carried out at definite temperature and two other extractions are carried out at definite temperature with reflux condenser. Proposed method provides increasing the yield of the end product from rosewort rhizomes and reducing duration of the technological process.

EFFECT: improved preparing method.

3 tbl, 3 ex

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RU 2 288 733 C1

Authors

Kurkin Vladimir Aleksandrovich

Dubishchev Aleksej Vladimirovich

Ezhkov Vladimir Nikolaevich

Titova Irina Nikolaevna

Dates

2006-12-10—Published

2005-08-08—Filed