AGENT FOR TREATMENT AND PROPHYLAXIS OF ACUTE PANCREATITIS AND METHODS FOR ITS USING Russian patent published in 2007 - IPC A61K39/395 A61P1/18 A61P1/00 

FIELD: medicine, surgery.

SUBSTANCE: invention relates to treatment and prophylaxis of acute pancreatitis in humans and agent used for this aim. Agent represents serum against true viper venom. Method involves preliminary administration in a patient of anti-histamine preparation and in 30 min serum is administrated. Serum is diluted with physiological solution and administrated by intravenous route by drops being firstly in dose 0.1 ml, then in 10 min in dose 0.25 ml, and then in 15 min - the remainder dose. In treatment of acute pancreatitis method involves administration of serum in dose 450 AE diluted in 300 ml of physiological solution in the first day, 300 AE of serum diluted in 200 ml of physiological solution in the second day and 150 AE of serum diluted in 100 ml of physiological solution in the third day. Prophylaxis of acute pancreatitis in humans is carried out by administration of 150 AE of seum diluted in 100 ml of physiological solution. Invention provides inhibition of enzymatic activity of pancreas that enhances effectiveness of treatment in case of severe forms of pancreatitis in edema and necrosis stage also, and promotes to prophylaxis of acute pancreatitis after direct surgery operations on pancreas and carrying out endoscopy in cholangiopancreatography procedure.

EFFECT: enhanced effectiveness of treatment and prophylaxis, valuable medicinal properties of agent.

3 cl, 4 ex