COMPOSITION AND METHOD FOR IMMUNIZATION, METHOD FOR PRODUCING OF NON-NATURAL, ORDERED AND REPEATED ANTIGEN MASSIVE Russian patent published in 2007 - IPC A61K39/00 

Abstract RU 2294211 C2

FIELD: molecular biology, virology, immunology, medicine.

SUBSTANCE: composition for immunization is disclosed. Claimed composition contains non-natural molecular carcass and antigen or antigen determinant. Non-natural molecular carcass contains core particle bound to organizer comprising the first binding site. Antigen or antigen determinant represents amyloidal beta-peptide (Aβ1-42) or fragment thereof and comprises the second bounding site, wherein antigen or antigen determinant and molecular carcass interact via binding to produce ordered and repeated antigen massive. Also disclosed are pharmaceutical composition, method for immunization, method for production of non-natural, ordered and repeated antigen massive. Present invention is useful in vaccine production, allergy treatment, prophylaxis and treatment of malignant tumors, end effective inducing of specific immune responses.

EFFECT: improved compositions for vaccine production.

31 cl, 62 dwg, 1 tbl, 59 ex

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RU 2 294 211 C2

Authors

Renner Vol'Fgang A.

Bakhmann Martin

Tisso Alen

Maurer Patrik

Lekhner Frantsiska

Zebbel' Peter

Piossek Kristine

Ortmann Rajner

Ljuend Rajner

Shtaufenbil' Mattias

Frej Peter

Dates

2007-02-27Published

2002-01-21Filed