FIELD: molecular biology, virology, immunology, medicine, pharmacy.
SUBSTANCE: invention claims composition comprising non-natural molecular skeleton and antigen or antigenic determinant. Non-natural molecular skeleton comprises RNA-containing phage bound with an organizing agent including the first binding site. Antigen or antigenic determinant comprises the second binding site. Antigen or antigenic determinant and molecular skeleton interacts by binding to form the ordered and repeated massive of antigens. Also, invention proposes pharmaceutical composition, immunization method, method for producing non-natural, ordered and repeated massive of antigens and coat protein. Invention can be used in preparing vaccines, in treatment of allergy, prophylaxis and treatment of malignant tumors and for effective inducing specific autoimmune responses.
EFFECT: valuable medicinal properties of composition.
42 cl, 62 dwg, 1 tbl, 59 ex
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Authors
Dates
2007-03-27—Published
2002-01-21—Filed