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2 376 307

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IPC

C07D487/04(2006-01-01)

A61K31/53(2006-01-01)

A61P31/12(2006-01-01)

(21) (22)

Application

2008121407/04, 2008-05-27

(24)

Start date

2008-05-27

(22)

Actual filing date

2008-05-27

(45)

Published

2009-12-20

(72)

Inventor

Chupakhin Oleg NikolaevichRusinov Vladimir LeonidovichUlomskij Evgenij NartsissovichCharushin Valerij NikolaevichShestakova Tat'Jana SergeevnaDeev Sergej LeonidovichRusinova Larisa IvanovnaAndronova Valerija L'VovnaGalegov Georgij Artem'EvichKarpenko Inna LeonidovnaJas'Ko Maksim VladimirovichKukhanova Marina Konstantinovna

(73)

Holder

Institut Organicheskogo Sinteza Im. I.Ja. Postovskogo Ural'Skogo Otdelenija Rossijskoj Akademii Nauk

4-((Z)-4'-HYDROXYBUTENE-2'-YL)-2-R-6-FURYL-1,2,4-TRIAZOLO[5,1-c][1,2,4]TRIAZINE-7-ONS Russian patent published in 2009 - IPC C07D487/04 A61K31/53 A61P31/12

Abstract RU 2376307 C1

FIELD: medicine.

SUBSTANCE: invention is related to 4-((2)-4'-hydroxybutene-2'-yl)-2-R-6-phenyl-1,2,4-triazolo[5,1-c][1,2,4]triazine-7-ons of common formula (1) ,

where R=H, CH₃,SCH₃ have antiviral action against herpesvirus of simple type 1 (HSV-1).

EFFECT: new derivatives have useful biological properties.

1 tbl

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RU 2 376 307 C1

Authors

Chupakhin Oleg Nikolaevich

Rusinov Vladimir Leonidovich

Ulomskij Evgenij Nartsissovich

Charushin Valerij Nikolaevich

Shestakova Tat'Jana Sergeevna

Deev Sergej Leonidovich

Rusinova Larisa Ivanovna

Andronova Valerija L'Vovna

Galegov Georgij Artem'Evich

Karpenko Inna Leonidovna

Jas'Ko Maksim Vladimirovich

Kukhanova Marina Konstantinovna

Dates

2009-12-20—Published

2008-05-27—Filed