METHOD FOR PURIFYING 5-AMINOLEVULINIC 5-AMINO-4-OXOPENTAENIC) ACID HYDROCHLORIDE Russian patent published in 2007 - IPC C07C227/38 C07C229/22 C07C227/12 

FIELD: organic chemistry, biochemistry, chemical technology.

SUBSTANCE: invention relates to a method for purification of synthetic 5-aminolevulinic (5-amino-4-oxopentaenic) acid hydrochloride (5-ALA) representing endogenous substance and biological precursor of porphyrines in living organism and plants. Preliminary purification of 5-ALA hydrochloride is carried out by electrodialysis of 5-ALA solutions with the concentration 140-300 g/l in current density 0.5-2.0 A/dm² and at temperature 20-30°C. Proposed method of purification of 5-ALA hydrochloride provides isolating expensive preparation from filtrates and to enhance the content of basic substance in technical 5-ALA hydrolyzate prepared by catalytic and electrochemical methods with the parent content of basic substance 87.0%, not above, that results to enhancing yield of final 5-ALA hydrochloride. Purified substance can be used in research and industrial practice.

EFFECT: improved purifying method.

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