TREATMENT OF NAIL INFECTION USING NO Russian patent published in 2007 - IPC A61K31/19 A61K31/60 A61K31/375 A61K33/00 A61K9/08 A61P31/10 

FIELD: medicine, dermatology.

SUBSTANCE: invention relates to using nitrogen oxide-producing components used for manufacturing a medicinal agent used in treatment or prophylaxis of subnail infection. Components comprise nitrite and organic acid. Before using each of indicated components is placed separately of one another. Nitrite is chosen from alkaline metal nitrites and earth-alkaline metal nitrites. Acid is chosen from formic acid, malic acid, maleic acid, acetic acid, lactic acid, citric acid, benzoic acid, tartaric acid, salicylic acid, ascorbic acid and their mixtures. At applying of indicated components on infected nail formed nitrogen oxides are able to penetrate through nail in the therapeutically effective dose. The effectiveness treatment index is similar or better as compared with oral treatment method but it shows lesser limitations with respect to safety including hepatotoxicity, severe cutaneous responses and interactions with other drugs.

EFFECT: improved method of treatment.

33 cl, 13 dwg, 16 tbl, 15 ex