METHOD FOR TREATMENT OF PULMONARY ORGANS TUBERCULOSIS Russian patent published in 2007 - IPC A61K31/4409 A61K31/395 A61K31/7036 A61K31/685 A61P31/06 A61M3/02 

FIELD: medicine, phthisiology.

SUBSTANCE: method involves the combined oral and rectal administration of chemopreparations. Ethambutol and pyrazinamide are administrated by oral route in the doses 1.2 g and 1.5 g, respectively. Mixture of chemopreparations as an ultraemulsion is used for rectal administration that is prepared 1 h before administration. The mixture comprises isoniazid (10 mg/kg), rifampicin (600 mg), kanamycin (1 g) and lecithin (20 ml). Therapy is carried out in intensive treatment phase 5 times per a week up to three months and in supporting phase 2 times per a week up to closing destruction cavities. Method provides rapid regression of pulmonary tuberculosis process, to improve tolerance of chemopreparations based on their selective accumulation in lymphatic system of lungs and specific schedule of administration of these chemopreparations. Invention can be used in treatment of destructive form of pulmonary tuberculosis.

EFFECT: improved method of treatment.

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