DERIVATIVES OF ALKYLUREA POSSESSING PROPERTY OF RETINOID AGONIST, PHARMACEUTICAL COMPOSITION AND MEDICINAL AGENT Russian patent published in 2007 - IPC C07C275/42 A61K31/192 A61P17/00 A61P35/00

Abstract RU 2299877 C2

FIELD: organic chemistry, medicine, pharmacy.

SUBSTANCE: invention relates to novel derivatives of alkylurea of the formula (I): or its pharmaceutically acceptable salt, solvate or hydrate possessing properties of retinoid agonists (RAR), pharmaceutical compositions and medicinal agent. In compound of the formula (I): n means a whole number from 0 to 2; X means oxygen atom (O); Y means -OR⁵ wherein R⁵ means hydrogen atom; R¹ means (C₂-C₈)-alkyl; R² means hydrogen atom, alkyl, hydroxy- or oxo-group; R⁹ means hydrogen atom.

EFFECT: valuable medicinal properties of compound and pharmaceutical composition.

12 cl, 3 sch, 10 tbl, 20 ex

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RU 2 299 877 C2

Authors

Belloni Pola Nanette

Kertesh Denis Dzhon

Klaus Mikhaehl'

Lap'Er Zhan-Mark

Dates

2007-05-27—Published

2002-09-11—Filed