FIELD: medicine. SUBSTANCE: described are new retinoic acid X-receptor ligands of formula I wherein R1-R7, R10, X and bond designated by dotted line are as defined in specification. Also described is pharmaceutical composition having antiproliferating activity and comprising compound of formula I and pharmaceutical carrier. Compound of formula I is selectively bonded with retinoid receptors R*R which is useful as antiproliferating agent for dermatological and oncological diseases. EFFECT: improved properties of the pharmaceutical composition. 19 cl, 3 dg, 6 dwg, 15 ex
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Authors
Dates
2000-03-10—Published
1995-07-29—Filed