FIELD: organic chemistry, chemical technology.
SUBSTANCE: invention relates to a method for synthesis of alkyl-ortho-nitrophenols. Invention describes a method for synthesis of alkyl-ortho-nitrophenols of the general formula: 
, wherein 1) R means hydrogen atom (H); R' means H; 2) R means H; R' means CH3; 3) R means CH; R' means H. Method is carried out by cyclization of isonitro-β-diketones with ketones followed by oxidation of formed nitrosophenols with hydrogen peroxide at temperature 30-40°C without their isolation. Method provides synthesis of alkyl-ortho-nitrophenols with required position of alkyl groups. Synthesized compounds can be used as semifinished substances in organic synthesis and analytical reagents.
EFFECT: improved method of synthesis.
3 tbl, 15 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PREPARING ALPHA-TOCOPHEROL (VITAMIN E) | 1998 |
|
RU2163600C2 |
| HEXASUBSTITUTED PARA-AMINOPHENOLS WITH ESTER GROUPS IN 2,6-POSITIONS RELATIVE HYDROXYL GROUP | 2009 |
|
RU2410371C1 |
| METHOD FOR PREPARING SUBSTITUTED N-ADAMANTYL-PARA-NITROSOARYLAMINES | 2005 |
|
RU2298544C1 |
| HEXASUBSTITUTED PARA-AMINOPHENOLS WITH ARYLAMIDE GROUPS IN 2,6 POSITIONS WITH RESPECT TO HYDROXYL | 2013 |
|
RU2537398C1 |
| METHOD OF PREPARING DIARYLSUBSTITUTED N-NITROSOPHENOLS | 0 |
|
SU897768A1 |
| METHOD OF PREPARING NITROSOPHENOLS | 0 |
|
SU726082A1 |
| METHOD OF SYNTHESIS OF SUBSTITUTED N-ALKYL-p- NITROSODIPHENYL AMINES | 1998 |
|
RU2139274C1 |
| METHOD OF PRODUCING SUBSTITUTED 2,3,5,6-TETRAOXABICYCLO[2,2,1]HEPTANES | 2012 |
|
RU2494102C1 |
| METHOD OF THE PRODUCTION OF PARA-ACETYLAMINOPHENOL | 2022 |
|
RU2800098C1 |
| METHOD OF PRODUCING DIETHYL ETHER OF 5-AMINO-2-HYDROXY-4,6-DIMETHYLISOPHTHALIC ACID | 2010 |
|
RU2446149C1 |
