FIELD: pharmacy.
SUBSTANCE: invention relates to medicinal agents, in particular, to a tablet degrading in the mouth cavity and containing the following components: 1) agent of benzimidazole type that inhibits activity of proton pump as microgranules covered by an enterosoluble envelope layer and covered additionally by at least one pH-dependent methacrylic copolymer-base barrier envelope; 2) at least one antacid as granule, and 3) mixture of excipients containing at least one loosing agent, one diluting agent, a lubricant and, possibly, agent promoting to swelling, agent promoting to penetrability, sweetening agents, correcting agents and dyes. Also, invention relates to methods for preparing a tablet and its using for treatment of digestive tract disorders. Invention provides prevention of dissolving and/or destruction of an enterosoluble envelope in mouth cavity or in stomach that is provided by applying definitive accessory substances of barrier envelope on an enterosoluble envelope for preparing a tablet degrading in mouth.
EFFECT: improved and valuable properties of preparation.
34 cl, 8 tbl, 7 ex
| Title |
Year |
Author |
Number |
| PHARMACEUTICAL COMPOSITION FOR TREATMENT OF GASTRIC AND DUODENUM ULCER IN FORM OF SOLID GELATIN CAPSULES, WHICH CONTAINS RABEPRAZOLE OR ITS DERIVATIVES, AND METHOD OF ITS OBTAINING |
2007 |
- Shobolov Dmitrij L'Vovich
- Papazova Natal'Ja Aleksandrovna
|
RU2414889C2 |
| PERORAL PHARMACEUTICAL MEDICINAL FORMS INCLUDING PROTON PUMP INHIBITOR AND ANTACID SUBSTANCE OR ALGINATE |
1996 |
- Depjui Ehlen
- Khal'Gren Agneta
|
RU2179453C2 |
| ORAL PHARMACEUTICAL MEDICINAL FORM WITH DISCRETE RELEASE |
1998 |
- Lundberg Per Jokhan
- S'Eblom Brita
|
RU2205028C2 |
| PHARMACEUTICAL COMPOSITIONS OF ACOTIAMIDE AND PROTON PUMP INHIBITOR |
2019 |
- Kanagasabapathy, Yuvaneshwari
- Venugopal, Hariharan
- Ayachi, Nidhish
- Gangwal, Rahul Prakash
- Maharana, Rajib Lochan
- Raut, Prashant Popatrao
- Srivastava, Saurabh
- Choudhury, Anup Avijit
- Raghuvanshi, Rajeev
|
RU2820820C2 |
| COMPOSITION INHIBITING SECRETION OF ACID IN STOMACH |
2003 |
- Pettersson Anders
- Njustrem Krister
- Khokansson Ivonne
|
RU2340358C2 |
| PHARMACEUTICAL MEDICINAL FORMS FOR ORAL INTAKE CONTAINING INHIBITOR OF PROTON PUMP AND AGENT FOR NONSTEROID ANTI-INFLAMMATORY THERAPY |
1996 |
- Ehlen Depjui
- Per Jokhan Lundberg
|
RU2158138C2 |
| PHARMACEUTICAL COMPOSITION WITH ENTEROSOLUBLE COATING, METHOD OF ITS PREPARING, METHOD OF TREATMENT OF PATIENTS |
1994 |
- Inga Siv Vengtsson
- Kurt Ingmar Levgren
|
RU2138254C1 |
| METHOD OF OBTAINING ENTERIC COATED GRANULES CONTAINING PROTON PUMP INHIBITOR, AND PHARMACEUTICAL COMPOSITIONS, CONTAINING MULTIPLE PARTICLES AND SUCH GRANULES |
2015 |
|
RU2679652C1 |
| SOLID MEDICINAL FORM, CONTAINING PROTON PUMP INHIBITOR, AND SUSPENSION OBTAINED FROM IT |
2005 |
|
RU2397756C2 |
| POWDER-LIKE ANTACIDE PHARMACEUTICAL COMPOSITION, PHARMACEUTICAL PREPARATION CONTAINING IT AND METHOD OF OBTAINING IT |
2007 |
|
RU2351332C2 |
