N-SUBSTITUTED ADENINE-BASED HETEROCYCLIC COMPOUNDS, THEIR USE IN PRODUCTION OF MEDICAMENTS, COSMETICS, GROWTH REGULATORS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS OR GROWTH REGULATORS BASED THEREON Russian patent published in 2007 - IPC C07D473/34 A61K8/49 A61K31/52 A01N43/92 A01N43/90 A61P3/10 A61P17/06 A61P19/02 A61P25/28 A61P33/14 

Abstract RU 2302421 C2

FIELD: synthesis of biologically active compounds.

SUBSTANCE: invention provides novel N6-substituted adenine-based heterocyclic compounds depicted by general formula I: , for which meanings of radicals are presented in description, and pharmaceutically acceptable salts thereof manifesting anticancer, mitotic, immunosuppressive, and antiaging activities for vegetable, animal, and human cells, and methods for preparation thereof. Included are also pharmaceutical compositions, cosmetic preparations, and growth regulators, which contain indicated derivatives as active components. Application of indicated derivatives for preparing therapeutical preparations, and cosmetic preparations are also described.

EFFECT: expanded synthetic possibilities in adenine series and increased choice of various biologically active agents.

10 cl, 10 dwg, 9 tbl, 14 ex

Similar patents RU2302421C2

Title Year Author Number
3-AMINOPYRROLIDONE DERIVATIVES 2004
  • Taler Florian
  • Sabido David Chibehle Marija
  • Maehstroni Sara
  • Ravel'Ja Luka Franchesko
  • Sal'Vati Patrisija
RU2395495C2
SUBSTITUTED GLUTARAMIDES, METHODS FOR THEIR PREPARING AND MEDICINAL AGENT BASED ON THEREOF 2001
  • Germann Tino
  • Frosh Shtefani
  • Vejd Ehrik
  • Bushmann Khel'Mut
  • Tsimmer Oval'D
RU2278857C2
N-ACYL-N' -BENZYLALYLENEDIAMNO DERIVATIVES 2004
  • Taler Florian
  • Sabido David Chibele Marija
  • Faravelli Laura
  • Gal'Jardi Stefanija
  • Kolombo Elena
  • Sal'Vati Patrichija
RU2387636C2
THIENOPYRIMIDINES, METHOD OF THEIR SYNTHESIS (VERSIONS), PHARMACEUTICAL COMPOSITION AND METHOD OF ITS PREPARING 1997
  • Rokhus Jonas
  • Shelling P'Er
  • Kluksen Frants-Verner
  • Kristadler Marija
RU2199541C2
THIENOPYRIMIDINES WITH INHIBITORY EFFECT WITH RESPECT TO PHOSPHODIESTERASE V (PDE V), METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION 1997
  • Jonas Rokhus
  • Shelling Pirre
  • Khrishtadler Maria
  • Kluksen Frants-Verner
RU2197492C2
0
  • Iogannes Kekk
  • Klaus-Rejnkhold Nol
  • Khelmut Piper
  • Gerd Kryuger
  • Zigfrid Pyushmann
SU523634A3
METHOD OF OBTAINING BENZYLAMINE DERIVATIVES OR SALTS THEREOF 0
  • Iogannes Kekk
  • Klaus-Rejnkhold Nol
  • Khelmut Piper
  • Gerd Kryuger
  • Zigfrid Pyushmann
SU640657A3
0
  • Iogannes Kekk
  • Klaus-Rejnkhold Nol
  • Khelmut Piper
  • Gerd Kryuger
  • Zigfrid Pyushmann
SU521838A3
0
  • Iogannes Kekk
  • Klaus-Rejnkhold Nol
  • Khelmut Piper
  • Gerd Kryuger
  • Zigfrid Pyushmann
SU521837A3
0
  • Iogannes Kekk
  • Klaus-Rejnkhold Nol
  • Khelmut Piper
  • Gerd Kryuger
  • Zigfrid Pyushmann
SU528866A3

RU 2 302 421 C2

Authors

Dolezal Karel

Popa Igor'

Kholub Jan

Lenobel Rene

Verbrouk Stefaan

Strnad Miroslav

Dates

2007-07-10Published

2002-08-01Filed