N-ACYL-N' -BENZYLALYLENEDIAMNO DERIVATIVES Russian patent published in 2010 - IPC C07C233/36 C07D207/27 A61K31/165 A61K31/4015 

Abstract RU 2387636 C2

FIELD: chemistry.

SUBSTANCE: invention relates to compounds and use of N-acyl-N'-benzylalkylenediamino derivatives of general formula I, where A is a linear or branched C2-C3 alkyl; X is oxygen; R1 is a linear or branched C1-C8 alkyl, optionally substituted with phenyl, phenoxy or naphthyl; or benzyl optionally substituted on the phenyl ring with one or more substitutes selected from halogen, C1-C4 alkyl, trifluoromethyl, C1-C4alkoxy group; R2 and R3 independently represent hydrogen, C1-C3 alkyl, halogen or C1-C4 alkoxy group; R4 is hydrogen or methyl; R5is hydrogen; R6 is a linear or branched C1-C6 alkyl or bonded to R5 to form a pyrrolidin-2-one ring; an their pharmaceutically acceptable salts which are active as sodium and/or calcium channel modulators.

EFFECT: wider field of use of the compounds.

7 cl, 13 ex

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RU 2 387 636 C2

Authors

Taler Florian

Sabido David Chibele Marija

Faravelli Laura

Gal'Jardi Stefanija

Kolombo Elena

Sal'Vati Patrichija

Dates

2010-04-27Published

2004-11-12Filed