3-AMINOPYRROLIDONE DERIVATIVES Russian patent published in 2010 - IPC C07D207/273 A61K31/4015 A61P29/00 

FIELD: chemistry.

SUBSTANCE: present invention relates to compounds characterised by formula I, and their use as sodium and/or calcium channel modulators when treating a wide range of diseases, including cardio-vascular, inflammatory, eye, urological, metabolic and gastro-intestinal diseases, as sell as a method of producing formula I compounds and pharmaceutical compositions based on formula I compounds. , where m equals 1-3, X is -CH₂-, O, S or NR⁶; R¹ is a possibly substituted alkyl, alkenyl or alkynyl, phenyl, benzyl, phenoxy or naphthyl; R², R³ represent hydrogen, alkyl, halogen, trifluoromethyl, hydroxy or alkoxy; R⁴, R⁵, R⁶ represent hydrogen or alkyl.

EFFECT: obtaining of novel biologically active compounds and pharmaceutical compositions based on the said compounds.

7 cl, 13 ex