FIELD: pharmaceutical industry, in particular production of anti-tumor and anti-HIV agents.
SUBSTANCE: claimed method includes reduction of betulonic acid with sodium borohydride in mixture of water and benzene in presence of phase transfer catalyst such as quaternary ammonium salt for 2 hours.
EFFECT: more effective method; increased yield of target product; decreased sodium borohydride consumption.
2 cl, 4 ex
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Authors
Dates
2007-08-27—Published
2006-04-03—Filed