FIELD: natural compounds, chemical technology.
SUBSTANCE: invention relates to the improved method for preparing biologically active substances from products of chemical processing vegetable biomass, in particular, to a method for preparing betulinic acid from betuline. Method is carried out by oxidation of betuline with chrome anhydride in acetic acid to betulonic acid, and reduction of betulonic acid with sodium boron hydride is carried out in diethyl ether solution being without its preliminary isolation. Invention provides enhanced yield, simplifying technology, decrease of the process time and decreasing set of solvents used.
EFFECT: improved preparing method.
1 cl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREPARING BETULINIC ACID | 2003 |
|
RU2246500C1 |
| METHOD OF SYNTHESIS OF BETULINIC ACID | 2001 |
|
RU2190622C1 |
| METHOD OF OBTAINING BETULINIC ACID | 2011 |
|
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|
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| METHOD FOR PRODUCING BETULINIC ACID | 2011 |
|
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| METHOD FOR OBTAINING BETULONIC ACID | 2007 |
|
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| METHOD FOR PRODUCING BETULONIC ACID | 2014 |
|
RU2568881C1 |
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|
RU2580106C1 |
| METHOD FOR PREPARING BETULINIC ACID FROM BETULONIC ACID | 2004 |
|
RU2271364C1 |
| METHOD FOR PRODUCTION OF BETULINIC ACID | 2006 |
|
RU2305106C1 |
