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(19)

RU

(11)

2 306 309

(13)

C2

(51)

IPC

C07D207/27(2006-01-01)

C07D409/06(2006-01-01)

C07D417/06(2006-01-01)

A61K31/4015(2006-01-01)

A61K31/4025(2006-01-01)

A61P37/02(2006-01-01)

A61P1/16(2006-01-01)

A61P7/00(2006-01-01)

A61P29/00(2006-01-01)

A61P15/10(2006-01-01)

A61P11/00(2006-01-01)

A61P19/00(2006-01-01)

A61P13/12(2006-01-01)

(21) (22)

Application

2004129584/04, 2003-03-04

(24)

Start date

2003-03-04

(22)

Actual filing date

2003-03-04

(45)

Published

2007-09-20

(72)

Inventor

Tani KousukeKobajasi KaoruMarujama ToruKambe TokhruOgava MikioSiroja Tsutomu

(73)

Holder

Ono Farmas'Jutikal Ko., Ltd.

8-AZAPROSTAGLANDINE DERIVATIVES, PHARMACEUTICAL COMPOSITION AND AGENT FOR PROPHYLAXIS OF DISEASES Russian patent published in 2007 - IPC C07D207/27 C07D409/06 C07D417/06 A61K31/4015 A61K31/4025 A61P37/02 A61P1/16 A61P7/00 A61P29/00 A61P15/10 A61P11/00 A61P19/00 A61P13/12 

Abstract RU 2306309 C2

FIELD: organic chemistry, pharmaceuticals.

SUBSTANCE: Described are derivatives of general formula I (all symbols are as described in specification), pharmaceutically acceptable salts thereof or cyclodextrin clathrates. Such compounds hardly bind of EP2 subtype of PGE receptor and are useful in prophylaxis of immune diseases, allergy, death of neuronal cells, liver or kidney insufficiency, etc.

EFFECT: new agent for prophylaxis of various diseases.

18 cl, 388 ex, 68 tbl, 3 dwg

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RU 2 306 309 C2

Authors

Tani Kousuke

Kobajasi Kaoru

Marujama Toru

Kambe Tokhru

Ogava Mikio

Siroja Tsutomu

Dates

2007-09-20—Published

2003-03-04—Filed

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