FIELD: organic chemistry, pharmaceuticals.
SUBSTANCE: invention relates to lysine or proline L-ascorbic acid derivatives and methods for production thereof. Method for production of lysine L-ascorbic acid derivatives includes treatment of L-ascorbic acid with lysine followed by isolation of said target derivatives, wherein L-ascorbic acid is covalently bonded to lysine in C6-site of L-ascorbic acid. Method for production of proline L-ascorbic acid derivatives includes treatment of L-ascorbic acid with proline covalently bonded to L-ascorbic acid followed by isolation of said target derivatives.
EFFECT: new L-ascorbic acid derivatives useful in medicine as anticancer agents.
14 cl, 16 dwg, 8 ex
Authors
Dates
2007-10-27—Published
2002-08-23—Filed