NEW ASCORBIC ACID DERIVATIVES METHOD FOR PRODUCTION AND USES THEREOF Russian patent published in 2007 - IPC C07D307/32 A61K31/375 A61K31/34 

Abstract RU 2309152 C2

FIELD: organic chemistry, pharmaceuticals.

SUBSTANCE: invention relates to lysine or proline L-ascorbic acid derivatives and methods for production thereof. Method for production of lysine L-ascorbic acid derivatives includes treatment of L-ascorbic acid with lysine followed by isolation of said target derivatives, wherein L-ascorbic acid is covalently bonded to lysine in C6-site of L-ascorbic acid. Method for production of proline L-ascorbic acid derivatives includes treatment of L-ascorbic acid with proline covalently bonded to L-ascorbic acid followed by isolation of said target derivatives.

EFFECT: new L-ascorbic acid derivatives useful in medicine as anticancer agents.

14 cl, 16 dwg, 8 ex

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RU 2 309 152 C2

Authors

Rat Mattias

Nedzvetski Aleksandra

Ivanov Vadim

Netke Shrirang

Rumi M. Vakhid

Dates

2007-10-27Published

2002-08-23Filed