FIELD: chemistry; biochemistry.
SUBSTANCE: present invention pertains to biotechnology and is an oligopeptide, capable of blocking invasion and metastasis of cancerous cells, containing an oligopeptide series (given in the application) or its fragment. The invention is also a pharmaceutical composition for preventing or treating degenerative diseases, or pathological conditions, caused by destruction of the extracellular matrix (ECM) by matrix metalloproteinase (MMP), and a diagnostic composition for diagnosing degenerative diseases or pathological conditions, caused by destruction of the extracellular matrix (ECM) by matrix metalloproteinase (MMP). The invention is also a vaccine for treating or preventing degenerative diseases, or pathological conditions, caused by destruction of extracellular matrix (ECM) by matrix metalloproteinase (MMP).
EFFECT: provision for oligpeptides, which can effectively block invasion or metastasis of cancerous cells and which can be used for preventing or treating degenerative diseases or pathological conditions, caused by destruction of extracellular matrix by matrix metalloproteinase.
8 cl, 4 dwg, 1 tbl, 5 ex
