FIELD: organic chemistry, medicine, hepatology.
SUBSTANCE: invention proposes using 2-amino-7-bromo-4-acetylthiazolo[5,4-b]indole hydrobromide of the formula (I) as a substance protecting liver against poisoning with carbon tetrachloride and/or possessing prophylactic effect in lung toxic edema. Invention provides enhancing degree of liver protection against poisoning with carbon tetrachloride, decreasing expression of lung edema by the pulmonary coefficient and enhancing viability of animals (with respect to control).
EFFECT: valuable medicinal property of substance.
2 tbl
Title |
Year |
Author |
Number |
USE OF 2-AMINO-7-BROMO-4-ACETYLAZO[5,4-b]INDOL TO PROTECT ORGANISM AGAINST HYPERBARIC AND HEMATIC HYPOXIA AND/OR LIVER AGAINST CARBON TETRACHLORIDE POISONING |
2004 |
- Marysheva Vera Vasil'Evna
- Shabanov Petr Dmitrievich
- Gavrev Aleksej Ivanovich
|
RU2318828C2 |
2-AMINO-4-ACETYL-7-BROMO-8-HYDROXY-3,8-DIHYDROXYTIAZOLO[5,4-b]INDOLE FOR LIVER PROTECTION FROM POISONING WITH CARBON TETRACHLORIDE |
2004 |
- Marysheva Vera Vasil'Evna
- Shabanov Petr Dmitrievich
|
RU2286348C2 |
USING 2-AMINO-4-ACETYLTHIAZOLO[5,4-b]INDOLE FOR LIVER PROTECTION AGAINST POISONING WITH CARBON TETRACHLORIDE |
2004 |
- Marysheva Vera Vasil'Evna
- Shabanov Petr Dmitrievich
|
RU2309743C2 |
2-AMINO-4-ACETYL-7-BROMO-8-HYDROXY-3,8-DIHYDROTHIAZOLO[5,4-b]INDOLE HYDROBROMIDE PROTECTING BODY AGAINST HYPOXIA AND LIVER AGAINST POISONING WITH CARBON TETRACHLORIDE |
2004 |
- Marysheva Vera Vasil'Evna
- Shabanov Petr Dmitrievich
|
RU2281949C2 |
2-AMINO-4-ACETYLTHIAZOLO[5,4-B]INDOLE PROTECTING BODY FROM EFFECT OF HYPOXIA AND TOXIC LUNG EDEMA |
2000 |
- Marysheva V.V.
- Shabanov P.D.
- Torkunov P.A.
- Zemljanoj A.V.
- Varlashova M.B.
|
RU2188824C1 |
2-AMINO-4-ACETYLTHIAZOLO[5,4-B]INDOLE HYDROBROMIDE PROTECTING LIVER AGAINST POISONING WITH CARBON TETRACHLORIDE AND A METHOD OF ITS SYNTHESIS |
1992 |
- Velezheva V.S.
- Mel'Man A.I.
- Tomchin A.B.
- Smirnov A.V.
- Okovityj S.V.
- Gajvoronskaja V.V.
|
RU2076867C1 |
APPLYING OF 2-AMINO-7-BROMO-4-ACETYLTHIAZOLO-[5,4-b]INDOLE HYDROBROMIDE FOR INCREASE OF WORKING CAPABILITY |
2007 |
- Marysheva Vera Vasil'Evna
- Gavrev Aleksej Ivanovich
- Shabanov Petr Dmitrievich
|
RU2339378C1 |
USE OF 2-AMINO-4-ACETYLTHIAZOLO[5,4-b]INDOLE HYDROBROMIDE FOR BODY PROTECTION AGAINST EFFECT OF HEMIC AND HYPERCAPNIC HYPOXIA |
2003 |
- Marysheva Vera Vasil'Evna
- Shabanov Petr Dmitrievich
|
RU2281095C2 |
7-BROMO-4-ACETYLTHIAZOLO[5,4-b]INDOL-2-SUCCINIMIDE PROTECTING BODY AGAINST HYPOXIA AND POSSESSING CURATIVE EFFECT IN LUNG TOXIC EDEMA |
2004 |
- Marysheva Vera Vasil'Evna
- Torkunov Pavel Anatol'Evich
- Shabanov Petr Dmitrievich
|
RU2281951C2 |
4-ACETYLTHIAZOLO[5,4-b]INDOL-2-SUCCINIMIDE PROTECTING BODY AGAINST HYPOXIA AND POSSESSING PROPHYLACTIC EFFECT IN LUNG TOXIC EDEMA |
2004 |
- Marysheva Vera Vasil'Evna
- Torkunov Pavel Anatol'Evich
- Shabanov Petr Dmitrievich
|
RU2281950C2 |